|
|
N-formyl-L-kynurenine + H2O <=> L-kynurenine + formate + H+
|
3.5.1.9
arylformamidase
|
–
|
BMK
|
|
BRENDA:
BR22715
KEGG:
R01959
MetaCyc:
ARYLFORMAMIDASE-RXN
SABIO-RK:
2006
|
|
|
|
L-kynurenine + H2O <=> H+ + L-alanine + anthranilate
|
3.7.1.3
kynureninase
|
–
|
BMK
|
|
BRENDA:
BR29549
KEGG:
R00987
MetaCyc:
KYNURENINASE-RXN
SABIO-RK:
1281
|
|
|
|
L-kynurenine + O2 + NADPH + H+ <=> L-3-hydroxykynurenine + H2O + NADP+
|
1.14.13.9
kynurenine 3-monooxygenase
|
–
|
BMK
|
|
BRENDA:
BR33724;
BS386517
KEGG:
R01960
MetaCyc:
KYNURENINE-3-MONOOXYGENASE-RXN
SABIO-RK:
2007
|
|
|
|
L-kynurenine + 2-oxoglutarate <=> L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.75
cysteine-conjugate transaminase
|
–
–
|
BMK
|
|
BRENDA:
BR47389
KEGG:
R01956
MetaCyc:
2.6.1.7-RXN
SABIO-RK:
2003
|
|
|
|
L-kynurenine + glyoxylate <=> glycine + 4-(2-aminophenyl)-2,4-dioxobutanoate
|
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.63
kynurenine---glyoxylate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
|
|
|
BRENDA:
BR47432
KEGG:
R01957
MetaCyc:
2.6.1.63-RXN
SABIO-RK:
2004
|
|
|
|
L-kynurenine + 2-oxoglutarate <=> Kynurenic_acid + L-glutamate + H2O
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
|
|
BRENDA:
BS353505
SABIO-RK:
14606
|
|
|
|
L-kynurenine + pyruvate <=> Kynurenic_acid + L-alanine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353514
SABIO-RK:
13965
|
|
|
|
L-kynurenine + oxaloacetate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + DL-aspartate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS377048
SABIO-RK:
12044
|
|
|
|
L-kynurenine + NADH + H+ + O2 <=> L-3-hydroxykynurenine + NAD+ + H2O
|
1.14.13.9
kynurenine 3-monooxygenase
|
–
|
|
|
BRENDA:
BS413433
SABIO-RK:
14357
|
|
|
|
L-kynurenine + FADH2 + Cl- + O2 + H+ <=> 5-chloro-L-kynurenine + FAD + 2 H2O
|
1.14.19.59
tryptophan 6-halogenase
|
–
|
|
|
BRENDA:
BS443670
|
|
|
|
L-kynurenine + FADH2 + Cl- + O2 + H+ <=> L-5-chloro-kynurenine + FAD + 2 H2O
|
1.14.19.58
tryptophan 5-halogenase
1.14.19.59
tryptophan 6-halogenase
|
–
–
|
|
|
BRENDA:
BS443669
|
|
|
|
L-kynurenine + 2-oxobutyrate <=> Kynurenic_acid + 2-aminobutanoate + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353513
|
|
|
|
L-kynurenine + 2-oxobutyrate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + 2-aminobutanoate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS377042
|
|
|
|
N-formyl-DL-kynurenine + H2O <=> L-kynurenine + formate + N-formyl-D-kynurenine
|
3.5.1.9
arylformamidase
|
–
|
|
|
BRENDA:
BS140698
|
|
|
|
N1,Nalpha-diformyl-L-kynurenine + H2O <=> formate + L-kynurenine
|
3.5.1.9
arylformamidase
|
–
|
|
|
BRENDA:
BS140699
|
|
|
|
L-kynurenine + 3-Indole-2-oxopropanoate <=> Kynurenic_acid + L-tryptophan + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353511
|
|
|
|
L-kynurenine + 4-hydroxyphenylpyruvate <=> Kynurenic_acid + L-tyrosine
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS423755
|
|
|
|
L-kynurenine + 4-methyl-2-oxopentanoate <=> Kynurenic_acid + DL-leucine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353509
|
|
|
|
L-kynurenine + 4-methyl-2-oxopentanoate <=> Kynurenic_acid + 2,4-dimethylvalerate + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353536
|
|
|
|
L-kynurenine + 4-methyl-2-oxopentanoate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS377045
|
|
|
|
L-kynurenine + 2-oxoisovalerate <=> Kynurenic_acid + DL-valine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353517
|
|
|
|
L-kynurenine + 2-Oxopentanoate <=> Kynurenic_acid + 2-aminopentanoate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS423753
|
|
|
|
L-kynurenine + 2-Oxohexanoate <=> Kynurenic_acid + 2-aminohexanoate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS423750
|
|
|
|
L-kynurenine + 3-methyl-2-oxopentanoate <=> Kynurenic_acid + L-isoleucine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353518
|
|
|
|
L-kynurenine + 2-oxoadipate <=> Kynurenic_acid + 2-Aminoadipate + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353507
|
|
|
|
L-tryptophan + O2 <=> L-kynurenine
|
1.13.11.26
peptide-tryptophan 2,3-dioxygenase
1.13.11.52
indoleamine 2,3-dioxygenase
|
–
–
|
|
|
BRENDA:
BS288933
|
|
|
|
L-kynurenine + H2O <=> quinolinic_acid
|
3.7.1.3
kynureninase
|
–
|
|
|
BRENDA:
BS190207
|
|
|
|
L-kynurenine <=> kynuramine + CO2
|
4.1.1.28
aromatic-L-amino-acid decarboxylase
|
–
|
|
|
BRENDA:
BS1378
|
|
|
|
L-kynurenine + phenylpyruvate <=> L-phenylalanine + L-glutamate + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353537
|
|
|
|
L-kynurenine + 2-Oxopentanoate <=> Kynurenic_acid + L-norvaline + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353512
|
|
|
|
L-kynurenine + 2-Oxohexanoate <=> Kynurenic_acid + L-norleucine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353508
|
|
|
|
L-kynurenine + 3-Mercaptopyruvate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS377047
|
|
|
|
L-kynurenine + 4-methylsulfanyl-2-oxobutanoate <=> Kynurenic_acid + L-methionine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353515
|
|
|
|
L-kynurenine + 4-methylsulfanyl-2-oxobutanoate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine
|
2.6.1.63
kynurenine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS354010
|
|
|
|
L-kynurenine + Hydroxypyruvate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-serine
|
2.6.1.63
kynurenine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS354009
|
|
|
|
L-kynurenine + oxaloacetate <=> Kynurenic_acid + L-aspartate + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353506
|
|
|
|
L-kynurenine + glyoxylate <=> Kynurenic_acid + glycine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353516
|
|
|
|
L-kynurenine + glyoxylate <=> 3-(2-aminophenyl-)2,4-dioxobutanoate + glycine
|
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS354043
|
|
|
|
L-kynurenine + pyruvate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine
|
2.6.1.63
kynurenine---glyoxylate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
|
|
|
BRENDA:
BS354008
|
|
|
|
L-kynurenine + phenylpyruvate <=> Kynurenic_acid + L-phenylalanine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353510
|
|
|
|
L-kynurenine + phenylpyruvate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-phenylalanine
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS377049
|
|
|
|
2-oxoadipate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminoadipate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
SABIO-RK:
12043
|
|